Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Feb 11;18(5):225-6.

[Anti-cytoplasmic antibodies of neutrophil granulocytes in systemic vasculitis]

[Article in French]
J C Brugier  1 , G Touchard, D u Lê Thi Huong, Y Lebranchu, J L Preud'homme
Affiliations
  • PMID: 2564200

[Anti-cytoplasmic antibodies of neutrophil granulocytes in systemic vasculitis]

[Article in French]
J C Brugier et al. Presse Med. .

Abstract

Autoantibodies to the cytoplasmic components of neutrophil polymorphonuclear granulocytes (ACPA) were searched for by indirect immunofluorescence on ethanol-fixed smears from normal white blood cells in 248 sera from patients with Wegener's granulomatosis, Kawasaki disease and various other vasculitides, connective tissue diseases, nephropathies and infiltrative pulmonary diseases. Apart from a weak positivity in a few Kawasaki disease sera, ACPA were found in Wegener's granulomatosis (and micropolyarteritis) only, with a correlation between ACPA titers and disease activity. These results confirm the value of ACPA in the diagnosis and evaluation of activity of Wegener's granulomatosis.

PubMed Disclaimer

Publication types

LinkOut - more resources