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. 2015:2015:571965.
doi: 10.1155/2015/571965. Epub 2015 Jan 6.

Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience

Ji Hyuk Kang  1 , Yun Jeong Lim  1 , Jung Hyun Kang  1 , Jae Nam Yang  1 , Seung Min Shin  1 , Jae Hyeuk Choi  1 , Jin Ho Lee  1
Affiliations

Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience

Ji Hyuk Kang et al. Gastroenterol Res Pract. 2015.

Abstract

Aims. Gastric cancer is the second most prevalent cancer and the third leading cause of cancer-related deaths in Korea. The National Cancer Screening Program (NCSP) has implemented esophagogastroduodenoscopy (EGD) biennially for all Koreans starting in their 40s. This study was conducted to estimate the clinical relevance of NCSP through identifying the prevalence of gastric disease, including cancer. Materials and Methods. Data from 40,821 subjects who received the screening EGD in the single center for 7 years were retrospectively investigated. Results. The overall prevalence of nonatrophic/atrophic/metaplastic gastritis, peptic ulcer, adenoma, early gastric cancer (EGC), and advanced gastric cancer (AGC) was 44.28%, 27.97%, 14.95%, 0.59%, 0.43%, 0.21%, and 0.09%, respectively. The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women. The prevalence of preneoplastic/neoplastic disease significantly increased with age. Judged from the ratio of EGC to AGC, the proportion of EGC made up to 70% of all cancers. Conclusions. Screening endoscopy starting for people in their 40s should be strongly recommended for the elderly. Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.

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Figures

Figure 1
Figure 1
Overall prevalence of gastric diseases. EGC: early gastric cancer; AGC: advanced gastric cancer; PUD: peptic ulcer disease.
Figure 2
Figure 2
(a) Prevalence of gastric disease according to age distribution. (b) Prevalence of adenoma and gastric cancer according to age distribution.
Figure 3
Figure 3
Proportion of early gastric cancer and advanced gastric cancer among gastric cancer diagnosed through National Cancer Screening Program from October 2005 to April 2012. EGC: early gastric cancer; AGC: advanced gastric cancer.
Figure 4
Figure 4
Proportion of early gastric cancer and advanced gastric cancer according to screening interval for gastric cancer. EGD: esophagogastroduodenoscopy; EGC: early gastric cancer; AGC: advanced gastric cancer.
See this image and copyright information in PMC

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