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Review
. 2015 Mar;5(3):239-44.
doi: 10.1158/2159-8290.CD-14-1205. Epub 2015 Feb 2.

Therapeutic insights from genomic studies of head and neck squamous cell carcinomas

Peter S Hammerman  1 , D Neil Hayes  2 , Jennifer R Grandis  3
Affiliations
Review

Therapeutic insights from genomic studies of head and neck squamous cell carcinomas

Peter S Hammerman et al. Cancer Discov. 2015 Mar.

Abstract

Large and comprehensive genomic surveys of head and neck squamous cell carcinomas (HNSCC) are now greatly increasing our understanding of the diversity of this disease and the key genomic changes that drive these tumors. The results from these studies are beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we review some of the key findings from recent genomic studies of head and neck cancers, including the most comprehensive study to date from The Cancer Genome Atlas Network.

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Conflict of interest statement

The authors report no relevant conflicts of interest.

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