doi: 10.1093/cid/civ062.
Epub 2015 Feb 2.
Interleukin-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations
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- PMID: 25645216
- DOI: 10.1093/cid/civ062
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Interleukin-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations
Clin Infect Dis.
.
Free article
Abstract
Rhinoviruses cause the common cold and exacerbations of asthma. Animal models of infection have identified a protective role for interleukin-18 (IL-18). Following experimental rhinovirus infection, we observed increased respiratory symptoms in healthy and asthmatic subjects with low nasal and bronchial IL-18 levels.
Keywords: asthma; inflammasome; interleukin-18; rhinovirus infection.
© The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
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