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Review
. 2015 Apr;42(4):537-61.
doi: 10.1007/s00259-014-2984-3. Epub 2015 Feb 3.

Radiopharmaceuticals as probes to characterize tumour tissue

Israt S Alam  1 , Mubarik A Arshad, Quang-Dé Nguyen, Eric O Aboagye
Affiliations
Review

Radiopharmaceuticals as probes to characterize tumour tissue

Israt S Alam et al. Eur J Nucl Med Mol Imaging. 2015 Apr.

Abstract

Tumour cells exhibit several properties that allow them to grow and divide. A number of these properties are detectable by nuclear imaging methods. We discuss crucial tumour properties that can be described by current radioprobe technologies, further discuss areas of emerging radioprobe development, and finally articulate need areas that our field should aspire to develop. The review focuses largely on positron emission tomography and draws upon the seminal 'Hallmarks of Cancer' review article by Hanahan and Weinberg in 2011 placing into context the present and future roles of radiotracer imaging in characterizing tumours.

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