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Case Reports
. 2015 Jun;35(2):144-7.
doi: 10.1097/WNO.0000000000000217.

Ipilimumab-associated bilateral optic neuropathy

Oliver L Yeh  1 , Courtney E Francis
Affiliations
Case Reports

Ipilimumab-associated bilateral optic neuropathy

Oliver L Yeh et al. J Neuroophthalmol. 2015 Jun.

Abstract

Ipilimumab is a novel monoclonal antibody targeting the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) receptor that has been shown to improve survival in metastatic melanoma. Previous case reports have documented its association with drug-induced uveitis. We report a patient who developed bilateral optic neuropathy with disc edema while taking this medication.

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