Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Dec 30;4(2):151-7.
doi: 10.5681/hpp.2014.020. eCollection 2014.

Investigation of enrofloxacin and chloramphenicol residues in broiler chickens carcasses collected from local markets of tabriz, northwestern iran

Vahideh Ebrahimzadeh Attari  1 , Mehran Mesgari Abbasi  2 , Nasim Abedimanesh  1 , Alireza Ostadrahimi  3 , Abolfazl Gorbani  4
Affiliations

Investigation of enrofloxacin and chloramphenicol residues in broiler chickens carcasses collected from local markets of tabriz, northwestern iran

Vahideh Ebrahimzadeh Attari et al. Health Promot Perspect. .

Abstract

Background: The present study was aimed to determine the residual amounts of chloramphenicol and enrofloxacin in broiler chickens muscle and liver sam-ples gathered from local markets of Tabriz City, northwestern Iran.

Methods: Ninety broiler chickens carcasses were collected from different local markets of Tabriz, during July/August 2013. Random samples of thigh and breast muscle and liver were gathered and kept at -80(°)C until analyzes. The samples were then assayed using enzyme-linked immunosorbent assay (ELISA) according to the protocol of each antibiotic kit. Data were statistically analyzed using the computer program SAS 9.1.

Results: Eighty two samples (91/1 %) contained residues of enrofloxacin, alt-hough mean (±SD)of enrofloxacin concentration was lower than the European Union maximum residue limits(MRLs) value (P<0.001). Moreover, 28 (31/1 %) had detectable concentrations of chloramphenicol while it was not defined any MRLs value for chloramphenicol because its using has been forbidden in food animals.

Conclusion: The frequency of contamination with enrofloxacin was considerable for the analyzed samples. Furthermore, the existence of chloramphenicol in almost one third of samples seems to be a public health threat due to its illegal use in food animals including poultry.

Keywords: Antibiotic residues; Broiler chicken; Chloramphenicol; Enrofloxacin; MRLs.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Cinquina AL, Longo F, Anastasi G, Giannetti L, Cozzani R. Validation of a high-performance liquid chromatography method for the determination of oxytetracycline, tetracycline, chlortetracycline and doxycycline in bovine milk and muscle. J Chromatogr A. 2003;987:227–233. - PubMed
    1. Linton AH. Antibiotics, animals and man, An apprasial of a contentious subject. In:Woodbine M, editor. Antibiotics and Antibiosis in agriculture. London: Butterworths, Inc; 1977.
    1. Salehzadeh F, Madani R, Salehzadeh A, Rokni N, Golchinefar F. Oxytetracycline residue in chicken tissues from Tehran slaughterhouses in Iran. Pakistan J Nutr. 2006;5:377–381.
    1. Droumev D. Review of antimicrobial growth promoting agents available. Vet Res Commun. 1983;7:85–99. - PubMed
    1. Holt D, Harvey D, Hurley R. Chloramphenicol toxicity. Adverse Drug React Toxicol Rev. 1993;12:83–95. - PubMed

LinkOut - more resources