Strengthening routine immunization systems to improve global vaccination coverage
- PMID: 25649959
- PMCID: PMC10350316
- DOI: 10.1093/bmb/ldv001
Strengthening routine immunization systems to improve global vaccination coverage
Abstract
Background: Global coverage with the third dose of diphtheria-tetanus-pertussis vaccine among children under 1 year of age stagnated at ∼ 83-84% during 2008-13.
Sources of data: Annual World Health Organization and UNICEF-derived national vaccination coverage estimates.
Areas of agreement: Incomplete vaccination is associated with poor socioeconomic status, lower education, non-use of maternal-child health services, living in conflict-affected areas, missed immunization opportunities and cancelled vaccination sessions.
Areas of controversy: Vaccination platforms must expand to include older ages including the second year of life. Immunization programmes, including eradication and elimination initiatives such as those for polio and measles, must integrate within the broader health system.
Growing points: The Global Vaccine Action Plan (GVAP) 2011-20 is a framework for strengthening immunization systems, emphasizing country ownership, shared responsibility, equity, integration, sustainability and innovation.
Areas timely for developing research: Immunization programmes should identify, monitor and evaluate gaps and interventions within the GVAP framework.
Keywords: Expanded Programme on Immunization; global health; immunization; routine immunization; vaccination; vaccination coverage.
Published by Oxford University Press 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.
Conflict of interest statement
Conflict of Interest statement
The authors have no potential conflicts of interest.
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References
-
- Chan M Beyond expectations: 40 years of EPI. Lancet 2014;383:1697–8. - PubMed
-
- Mitchell V, Dietz V, Okwo-Bele JM, et al. Immunization in developing countries. In: Plotkin S, Orenstein W, Offit W (eds). Vaccine, 6th edn. Amsterdam: Elsevier Saunders, 2013, 1369–94.
-
- WHO/UNICEF. WHO and UNICEF estimates of coverage: 2013 revision. http://www.who.int/immunization/monitoring_surveillance/data/en/ (15 January 2015, date last accessed).
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