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Review
. 1989 Feb;14(2):52-6.
doi: 10.1016/0968-0004(89)90043-1.

Vertebrate homeodomain proteins: families of region-specific transcription factors

C V Wright, K W Cho, G Oliver, E M De Robertis
Review

Vertebrate homeodomain proteins: families of region-specific transcription factors

C V Wright et al. Trends Biochem Sci. 1989 Feb.

Abstract

Vertebrate homeodomain proteins are transcription factors whose genes can be isolated via a conserved DNA-binding domain called the homeobox. We review recent studies suggesting that one function of these genes is the early subdivision of the embryo along the antero-posterior axis into 'fields' of cells with different developmental potential.

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