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Comment
. 2015;14(3):295-6.
doi: 10.1080/15384101.2015.1006552.

The Yin and Yang of DAXX regulation

Keith W Caldecott  1
Affiliations
Comment

The Yin and Yang of DAXX regulation

Keith W Caldecott. Cell Cycle. 2015.
No abstract available

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Figures

Figure 1.
Figure 1.
Regulation of DAXX phosphorylation by the ATM/Wip1 Axis. ATM protein kinase and Wip1 protein phosphatase promote (green arrows) or reduce (red arrows) phosphorylation of p53 and DAXX, respectively. Notice the negative feedback loop linking p53 to Wip1 (yellow arrow) and by which p53 is autoregulated.
See this image and copyright information in PMC

Comment on

References

    1. Brazina J, et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. Cell Cycle. 2014; 14(3):397-91; http://dx.doi.org/ 10.4161/15384101.2014.988019 - DOI
    1. Salomoni P, Khelifi AF. Trends Cell Biol 2006; 16:97-104; PMID:16406523; http://dx.doi.org/ 10.1016/j.tcb.2005.12.002 - DOI - PubMed
    1. Zhu Y-H, Bulavin DV. Prog Mol Biol Transl Sci 2012; 106:307-25; PMID:22340722; http://dx.doi.org/ 10.1016/B978-0-12-396456-4.00001-8 - DOI - PubMed
    1. Eliaš J, et al. Biochim Biophys Acta 2014; 1844:232-47; PMID:24113167; http://dx.doi.org/ 10.1016/j.bbapap.2013.09.019 - DOI - PubMed

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