Dysbiosis of the gut microbiota in disease
- PMID: 25651997
- PMCID: PMC4315779
- DOI: 10.3402/mehd.v26.26191
Dysbiosis of the gut microbiota in disease
Abstract
There is growing evidence that dysbiosis of the gut microbiota is associated with the pathogenesis of both intestinal and extra-intestinal disorders. Intestinal disorders include inflammatory bowel disease, irritable bowel syndrome (IBS), and coeliac disease, while extra-intestinal disorders include allergy, asthma, metabolic syndrome, cardiovascular disease, and obesity.
Keywords: Microbiome; colonic metabolome; gut health; gut–brain–axis; inflammation; short-chain fatty acids.
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