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Review
. 2014 Dec 22:11:45-51.
doi: 10.2147/TCRM.S76282. eCollection 2015.

Diagnosis and management of xerostomia and hyposalivation

Alessandro Villa  1 , Christopher L Connell  2 , Silvio Abati  3
Affiliations
Review

Diagnosis and management of xerostomia and hyposalivation

Alessandro Villa et al. Ther Clin Risk Manag. .

Abstract

Xerostomia, the subjective complaint of dry mouth, and hyposalivation remain a significant burden for many individuals. Diagnosis of xerostomia and salivary gland hypofunction is dependent upon a careful and detailed history and thorough oral examination. There exist many options for treatment and symptom management: salivary stimulants, topical agents, saliva substitutes, and systemic sialogogues. The aim of this review is to investigate the current state of knowledge on management and treatment of patients affected by xerostomia and/or hyposalivation.

Keywords: dry mouth; saliva stimulation; saliva substitutes; sialogogues.

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References

    1. Hopcraft MS, Tan C. Xerostomia: an update for clinicians. Aust Dent J. 2010;55(3):238–244. quiz 353. - PubMed
    1. van der Putten GJ, Brand HS, Schols JM, de Baat C. The diagnostic suitability of a xerostomia questionnaire and the association between xerostomia, hyposalivation and medication use in a group of nursing home residents. Clin Oral Investig. 2011;15(2):185–192. - PMC - PubMed
    1. Fox PC, van der Ven PF, Sonies BC, Weiffenbach JM, Baum BJ. Xerostomia: evaluation of a symptom with increasing significance. J Am Dent Assoc. 1985;110(4):519–525. - PubMed
    1. Humphrey SP, Williamson RT. A review of saliva: normal composition, flow, and function. J Prosthet Dent. 2001;85(2):162–169. - PubMed
    1. Pedersen AM, Bardow A, Jensen SB, Nauntofte B. Saliva and gastrointestinal functions of taste, mastication, swallowing and digestion. Oral Dis. 2002;8(3):117–129. - PubMed