Giant myxoid liposarcoma of descending mesocolon origin

Abstract

Liposarcomas are one of the most common primary lesions of the retroperitoneal region. They rarely exhibit intra-abdominal location. Because the symptoms emerge later on, they often remain unnoticed until they grow large. Our aim in this paper is to present a case of myxoid liposarcoma of descending mesocolon origin, 40 cm wide and weighing 7000 g, seen in a 47-year-old male patient. No cases at this weight and radius, originating from descending mesocolon, belonging to the myxoid sub-type, were found in our literature scan.

Keywords: liposarcoma; mesocolon; sarcoma.

Figure 1

Contrast enhanced axial (A, B), coronal (C), and sagittal (D) computerised tomography scan demonstrates the presence of a giant mass distending the abdomen and pelvis. Heterogeneously enhancing (black arrows in B) lesion placed anterior to the mesenteric vessels (arrows). Coronal image demonstrates the bowel loop (straddling sign) (arrows in C) and mesenteric fat (arrowhead in A) over the mass. Anterior compression of the renal veins and inferior vena cava (arrows in A, arrowheads in B, and arrows in D)

Figure 2

Macroscopic view of liposarcoma

Figure 3

A – Diffuse S-100 positivity in the tumour (immunoperoxidase stain, 200×). B – Spindle-ovoid shaped atypical cells within a myxoid stroma (H + E stain, 200×). C – Ki-67 staining (arrows) in the tumour (immunoperoxidase stain, 200×)