Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Dec;8(12):CD01-2.
doi: 10.7860/JCDR/2014/10597.5315. Epub 2014 Dec 5.

Lead poisoning mimicking acute porphyria!

Affiliations
Case Reports

Lead poisoning mimicking acute porphyria!

Akshatha L N et al. J Clin Diagn Res. 2014 Dec.

Abstract

We are presenting a case of a 13-year-old autistic boy whose urine porphyrin test came positive on three separate occasions. The child was brought to emergency department of Kasturba Medical College Hospital, Attavar, Mangalore, India, with fever and acute abdominal pain, with no previous history of any serious illness. Investigations revealed thalassemia trait,microcytic hypochromic anaemia while the other biochemical and haematological parameters were normal. False positive urine porphyrin test may be seen in porphyria induced by liver cancer, hepatitis and heavy metal poisoning such as lead, arsenic and mercury. Blood lead (PbB) level was 59.5μg/dl. Further evaluation revealed a daily consumption of native medicine in the form of syrup.

Keywords: Lead poisoning; Porphyria.

PubMed Disclaimer

References

    1. JM Lamon. Clinical aspects of porphyrin measurement, other than lead poisoning. Clin Chem. 1977;23(2):260–63. - PubMed
    1. BS Gillis, Z Arbieva, IM Gavin. Analysis of lead toxicity in human cells. BMC Genomics. 2012;13:344. - PMC - PubMed
    1. T Venkatesh. Editorial role of a clinical biochemist in evaluating the impact of lead poisoning. Indian J Clin Bio chem. 2013;28(1):1–2. - PMC - PubMed
    1. J McEwen, C Paterson. Drugs and false-positive screening tests for porphyria. Br Med J. 1972;1:421. - PMC - PubMed
    1. A Pagliuca, GJ Mufti, D Baldwin, AN Lestas, RM Wallis, AJ Bellingham. Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak. J Clin Pathol. 1990;43(4):277–81. - PMC - PubMed

Publication types

LinkOut - more resources