Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Dec;8(12):ZE14-7.
doi: 10.7860/JCDR/2014/9957.5272. Epub 2014 Dec 5.

Evolution of Barrier Membranes in Periodontal Regeneration-"Are the third Generation Membranes really here?"

George Sam  1 , Baiju Radhamoni Madhavan Pillai  2
Affiliations
Review

Evolution of Barrier Membranes in Periodontal Regeneration-"Are the third Generation Membranes really here?"

George Sam et al. J Clin Diagn Res. 2014 Dec.

Abstract

In the last decades, Guide Tissue Regeneration (GTR) technique has been applied for the treatment of various periodontal defects such as intrabony defects, furcation involvements and localized gingival recession defects. From early days of using membranes with the simple aim of minimizing toxic response in the host, membranes have come a long way. Third generation membranes not only act as barriers but also as delivery devices to release specific agents. Many clinical trials have focused on using membranes as delivery devices for antibiotics and growth factors. In this article we take a brief look at the evolution of barrier membranes and future avenues with regard to third generation membranes.

Keywords: Barrier membranes; Collagen membranes; Growth factors; Guided tissue regeneration.

PubMed Disclaimer

References

    1. Melcher AH. On the repair potential of periodontal tissues. J Periodontol. 1976;47(5):256–60. - PubMed
    1. Gottlow J. Guided tissue regeneration using bioresorbable and non-resorbable devices: initial healing and long-term results. J Periodontol. 1993;64(11 Suppl):1157–65. - PubMed
    1. Wang HL, MacNeil RL. Guided tissue regeneration. Absorbable barriers. Dent Clin North Am. 1998;42(3):505–22. - PubMed
    1. Nyman S, Gottlow J, Karring T, Lindhe J. The regenerative potential of the periodontal ligament. An experimental study in the monkey. J Clin Periodontol. 1982;9(3):257–65. - PubMed
    1. Aaboe M, Pinholt EM, Hjorting-Hansen E. Healing of experimentally created defects: a review. Br J Oral Maxillofac Surg. 1995;33(5):312–18. - PubMed