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. 1989 Jan;33(1):8-14.

Immunoblotting analysis of class-specific antibody response in patients with primary HSV infection

M Lehtinen  1 , V Koivisto, T Lehtinen, A Ylä-Outinen, U Romppanen, J Paavonen
Affiliations
  • PMID: 2565678

Immunoblotting analysis of class-specific antibody response in patients with primary HSV infection

M Lehtinen et al. Acta Virol. 1989 Jan.

Abstract

Class-specific immune response in acute herpes simplex virus (HSV) infections to individual virus specified polypeptide antigens was analysed by immunoblotting. The HSV specified glycoproteins B (gB), C (gC), and D (gD) were detected. IgG-antibody response was shown to develop to various other virus specific polypeptides as well. The IgM- and IgA-antibody responses remained restricted to only a few HSV specific proteins, namely VP 13 (80 kD), VP 20 (52 kD), and VP 23 (40 kD) and to the low molecular weight polypeptides.

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