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. 2015 Jan-Feb;60(1):107.
doi: 10.4103/0019-5154.147892.

Pyoderma gangrenosum in a patient with pemphigus vulgaris: an unusual association

Affiliations

Pyoderma gangrenosum in a patient with pemphigus vulgaris: an unusual association

Vinay Keshavamurthy et al. Indian J Dermatol. 2015 Jan-Feb.
No abstract available

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Figures

Figure 1
Figure 1
(a) Clinical photography showing a large necrotic ulcer, with purulent base and surrounding erythema over the anterolateral aspect of left thigh. A flaccid bulla can also be appreciated below the ulcer (arrow). (b) Clinical photography showing gingival erosions
Figure 2
Figure 2
(a) Photomicrography of lesional skin biopsy from ulcer margin showing necrotic epidermis with intense neutrophilic infiltrate and fibrin deposition, H and E × 10X. (b) Photomicrography of a lesional skin biopsy from flaccid vesicle showing suprabasal acantholysis with tomb stone arrangement of basal keratinocytes, H and E × 40X

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References

    1. Su WP, Davis MD, Weenig RH, Powell FC, Perry HO. Pyoderma gangrenosum: Clinicopathologic correlation and proposed diagnostic criteria. Int J Dermatol. 2004;43:790–800. - PubMed
    1. Nico MM, Hussein TP, Aoki V, Lourenço SV. Pyostomatitis vegetans and its relation to inflammatory bowel disease, pyoderma gangrenosum, pyodermatitis vegetans, and pemphigus. J Oral Pathol Med. 2012;41:584–8. - PubMed
    1. Oka M, Berking C, Nesbit M, Satyamoorthy K, Schaider H, Murphy G, et al. Interleukin-8 overexpression is present in pyoderma gangrenosum ulcers and leads to ulcer formation in human skin xenografts. Lab Invest. 2000;80:595–604. - PubMed
    1. Mortazavi H, Babaeijandaghi F, Akbarzadeh M, Rezaei N, Amirzargar AA, Daneshpazhooh M, et al. The influence of systemic therapy on the serum levels of IL-6 and IL-8 in pemphigus vulgaris. J Eur Acad Dermatol Venereol. 2013;27:387–90. - PubMed
    1. Keskin DB, Stern JN, Fridkis-Hareli M, Razzaque Ahmed A. Cytokine profiles in pemphigus vulgaris patients treated with intravenous immunoglobulins as compared to conventional immunosuppressive therapy. Cytokine. 2008;41:315–21. - PubMed

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