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Comment
. 2015 Feb 5;16(2):103-4.
doi: 10.1016/j.stem.2015.01.006.

SIRT1 synchs satellite cell metabolism with stem cell fate

Alberto Diaz-Ruiz  1 , Marta Gonzalez-Freire  1 , Luigi Ferrucci  1 , Michel Bernier  1 , Rafael de Cabo  2
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Comment

SIRT1 synchs satellite cell metabolism with stem cell fate

Alberto Diaz-Ruiz et al. Cell Stem Cell. .
Free article

Abstract

Metabolic reprogramming of muscle stem cells modulates myogenic cell fate. In this issue of Cell Stem Cell, Ryall et al. (2015) show that SIRT1, a NAD(+)-dependent histone deacetylase, acts as an epigenetic regulator that connects changes in satellite cell metabolism with changes in the transcriptional machinery toward myogenic commitment.

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