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Review
. 2015 Mar;44(3):203-11.
doi: 10.1016/j.jgyn.2014.12.011. Epub 2015 Feb 7.

[Methotrexate pharmacology]

[Article in French]
L Lagarce  1 , M Zenut  2 , P Lainé-Cessac  3
Affiliations
Review

[Methotrexate pharmacology]

[Article in French]
L Lagarce et al. J Gynecol Obstet Biol Reprod (Paris). 2015 Mar.

Abstract

Methotrexate is a folic acid analog, which is a thymidylate synthetase and dihydrofolate reductase inhibitor. It is used in oncology, dermatology and rheumatology and off labelling in the treatment of ectopic pregnancies. This paper is a review of methotrexate pharmacology with focus on data concerning ectopic pregnancies.

Keywords: Ectopic pregnancy; Grossesse extra-utérine; Methotrexate; Méthotrexate; Pharmacologie; Pharmacology.

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