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. 2014 Dec 15;7(12):5588-92.
eCollection 2014.

Comparison of long-term mortality of acute ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome patients after percutaneous coronary intervention

Lihui Ren  1 , Huiming Ye  2 , Ping Wang  2 , Yuxia Cui  3 , Shichang Cao  3 , Shuzheng Lv  3
Affiliations

Comparison of long-term mortality of acute ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome patients after percutaneous coronary intervention

Lihui Ren et al. Int J Clin Exp Med. .

Abstract

Background and aims: This study is to compare the short-term and long-term mortality in patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation acute coronary syndrome (NSTE-ACS) after percutaneous coronary intervention (PCI).

Methods and results: A total of 266 STEMI patients and 140 NSTE-ACS patients received PCI. Patients were followed up by telephone or at medical record or case statistics center and were followed up for 4 years. Descriptive statistics and multivariate survival analyses were employed to compare the mortality in STEMI and NSTE-ACS. All statistical analyses were performed by SPSS19.0 software package. NSTE-ACS patients had significantly higher clinical and angiographic risk profiles at baseline. During the 4-year follow-up, all-cause mortality in STEMI was significantly higher than that in NSTE-ACS after coronary stent placement (HR 1.496, 95% CI 1.019-2.197). In a landmark analysis no difference was seen in all-cause mortality for both STEMI and NSTE-ACS between 6 month and 4 years of follow-up (HR 1.173, 95% CI 0.758-1.813).

Conclusions: Patients with STEMI have a worse long-term prognosis compared to patients with NSTE-ACS after PCI, due to higher short-term mortality. However, NSTE-ACS patients have a worse long-term survival after 6 months.

Keywords: Coronary stent placement; long-term prognosis; long-term survival; mortality.

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Figures

Figure 1
Figure 1
Cumulative survival rate in 0-48 months determined by Kaplan-Meier method (Log Rank P = 0.037).
Figure 2
Figure 2
Cumulative survival rate in 6-48 months determined by Kaplan-Meier method (Log Rank P = 0.469).
See this image and copyright information in PMC

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