Relation between infection with a subtype of HPV16 and cervical neoplasia
- PMID: 2566780
- DOI: 10.1016/s0140-6736(89)92329-5
Relation between infection with a subtype of HPV16 and cervical neoplasia
Erratum in
- Lancet 1989 Oct 21;2(8669):996
Retraction in
-
Retraction: human papillomavirus subtype 16b.Lancet. 1989 Dec 23-30;2(8678-8679):1535. doi: 10.1016/s0140-6736(89)92987-5. Lancet. 1989. PMID: 2574815 No abstract available.
Abstract
A variant (HPV16b) of the previously described human papillomavirus (HPV)16 (now called HPV16a) has been identified by polymerase chain reaction assays. Compared with HPV16a, HPV16b has a 21bp deletion and several point mutations within the upstream regulatory region. All cervical carcinoma samples studied contained only HPV16a. HPV16b was found only rarely in cervical neoplasia but was common in the normal population.
Comment in
-
Subtypes of human papillomavirus 16 in cervical tissue.Lancet. 1989 Dec 2;2(8675):1342-3. Lancet. 1989. PMID: 2574295 No abstract available.
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