Web of the extended Myc network captures metabolism for tumorigenesis
- PMID: 25670077
- DOI: 10.1016/j.ccell.2015.01.004
Web of the extended Myc network captures metabolism for tumorigenesis
Abstract
In this issue of Cancer Cell, Carroll and colleagues describe the role of MondoA, a member of the Myc-Max-Mxd-Mxl transcription factor network (termed the extended Myc network herein), in Myc-mediated alterations in cancer cell metabolism and tumorigenesis.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis.Cancer Cell. 2015 Feb 9;27(2):271-85. doi: 10.1016/j.ccell.2014.11.024. Epub 2015 Jan 29. Cancer Cell. 2015. PMID: 25640402 Free PMC article.
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