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. 2015 Jun;36(6):1011-5.
doi: 10.1007/s10072-015-2104-6. Epub 2015 Feb 11.

Cerebrospinal fluid and lumbar puncture: the story of a necessary procedure in the history of medicine

Sandro Zambito Marsala  1 , Manuela Gioulis, Michele Pistacchi
Affiliations

Cerebrospinal fluid and lumbar puncture: the story of a necessary procedure in the history of medicine

Sandro Zambito Marsala et al. Neurol Sci. 2015 Jun.

Abstract

The aim of our work was to investigate the different historical stages that led gradually to the discovery of the anatomical structures that form and contain cerebrospinal fluid (CSF), until the Quincke idea, to collect the liquid directly at the lumbar level delivering to humanity a diagnostic tool present and absolutely irreplaceable in everyday clinical practice. This is done through consultation of all the historical medical literature, together with the critical examination of the original articles when available in the most rigorous chronological and speculative order, which enabled knowledge advancement.

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References

    1. Acta Neurol Scand. 1967;43:Suppl 28:1-136 - PubMed
    1. Br Heart J. 1980 Nov;44(5):560-9 - PubMed
    1. J Hist Neurosci. 1997 Dec;6(3):227-39 - PubMed
    1. Acta Neurol Belg. 1972 Jul-Aug;72(4):226-34 - PubMed
    1. J Med Biogr. 2011 May;19(2):63-9 - PubMed

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