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Review
. 2015 Jan-Feb;90(1):74-89.
doi: 10.1590/abd1806-4841.20153509.

Chronic urticaria in adults: state-of-the-art in the new millennium

Paulo Ricardo Criado  1 , Roberta Facchini Jardim Criado  1 , Celina Wakisaka Maruta  1 , Vitor Manoel Silva dos Reis  1
Affiliations
Review

Chronic urticaria in adults: state-of-the-art in the new millennium

Paulo Ricardo Criado et al. An Bras Dermatol. 2015 Jan-Feb.

Abstract

Chronic urticaria has been explored in several investigative aspects in the new millennium, either as to its pathogenesis, its stand as an autoimmune or auto-reactive disease, the correlation with HLA-linked genetic factors, especially with class II or its interrelation with the coagulation and fibrinolysis systems. New second-generation antihistamines, which act as good symptomatic drugs, emerged and were commercialized over the last decade. Old and new drugs that may interfere with the pathophysiology of the disease, such as cyclosporine and omalizumab have been developed and used as treatments. The purpose of this article is to describe the current state of knowledge on aspects of chronic urticaria such as, pathophysiology, diagnosis and the current therapeutic approach proposed in the literature.

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Conflict of interest statement

Conflict of interest: None

Figures

FIGURE 1
FIGURE 1
Method of execution of the autologous serum skin test
FIGURE 2
FIGURE 2
Sequential treatment of Chronic Urticaria (in steps)
See this image and copyright information in PMC

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