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. 2014 Nov-Dec;30(6):1243-6.
doi: 10.12669/pjms.306.5191.

Recurrence rate with use of intraoperative Mitomycin C versus Conjunctival Autograft following pterygium excision

Quratulain Paracha  1 , Mohammad Ayoob  2 , Zafar Dawood  3 , Sajid Ali Mirza  4
Affiliations

Recurrence rate with use of intraoperative Mitomycin C versus Conjunctival Autograft following pterygium excision

Quratulain Paracha et al. Pak J Med Sci. 2014 Nov-Dec.

Abstract

Objective s : To determine the recurrence rate following Conjunctival Autograft versus Mitomycin C for pterygium excision.

Methods: Fifty Patients in this Randomized Clinical Trial who underwent pterygium excision from July 2013 to October 2013 at Department of Ophthalmology, Ziauddin University Hospital, Keamari, Karachi were included. All patients underwent detailed ophthalmic examination before surgery. Few drops of lidocaine were instilled, subconjunctival xylocaine 2% was injected. The pterygium was then excised from bulabar conjunctiva and peeled off from the corneal surface. Mitomycin C was applied to bare sclera in group A and Conjunctival autograft taken from superior bulbar conjunctiva of same eye was sutured to the bare sclera in group B. Data for pterygium recurrence was collected and analyzed using SPSS version 17.

Results: Among the 50 patients operated 64% (n=32) were male and 36% (n=18) female. Their age ranged from 28 -58 years with mean age 44.8yrs. Right eye was affected in 54% (n= 27) patients and left in 46% (n= 23). In group "A" (intraoperative MMC) conjunctival granuloma was noted in 1(4%), pterygium recurrence 4(16%) and ocular irritation was experienced by 5 (20%) patients. In group "B" (CAG) graft retraction was seen in 2(8%), patients, 1(4%) patients experienced persistent redness over the grafted tissue and pterygium recurrence was seen in 2(8%) patient. All of them were followed at day 1, week1, week 4 and week 12.

Conclusion: Both Conjunctival Autograft and Mitomycin C are effective in reducing the recurrence of pterygium but CAG gives better cosmetic results, the only drawback with it is the duration of the procedure.

Keywords: Conjunctival Autograft; Mitomycin C; Pterygium.

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Figures

Fig 1
Fig 1
Peroperative: subconjunctival xylocaine 2% injected
Fig 2
Fig 2
Peroperative: Bare Sclera to apply MMC
Fig 3
Fig 3
6 weeks postoperative CAG (nasal pterygium)
Fig 4
Fig 4
3 Months postoperative CAG (temporal pterygium)
See this image and copyright information in PMC

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