Obstetric hemorrhage
- PMID: 25674990
- DOI: 10.1097/ACO.0000000000000168
Obstetric hemorrhage
Abstract
Purpose of review: To provide a review of the current literature on the management of obstetric hemorrhage.
Recent findings: Obstetric hemorrhage remains a prominent cause of maternal morbidity and mortality. When postpartum hemorrhage is refractory to manual and pharmacologic treatments, escalating interventions may be needed. Second-line interventions include the use of intrauterine balloon (or gauze) tamponade and uterine compression sutures. If these therapies fail to stop the bleeding, patients may need to undergo radiological embolization, pelvic devascularization, or hysterectomy. In recent years, pelvic arterial embolization has become a common treatment for intractable postpartum hemorrhage in an effort to avoid hysterectomy. The use of prophylactic arterial catheterization in the management of cases with expected major postpartum hemorrhage (e.g., placenta increta or percreta) has also been reported. However, the efficacy and safety of this technique requires further study.
Summary: Postpartum hemorrhage is best managed by using a stepwise progressive approach. Manual and pharmacologic interventions are first-line treatments. Second-line treatments are used when bleeding continues; and hysterectomy is reserved for only the most extreme cases. Outcomes may be improved by thorough preparation, anticipating the risk of obstetric hemorrhage, and coordinating consultants for interventional procedures.
Similar articles
-
Value of pelvic embolization in the management of severe postpartum hemorrhage due to placenta accreta, increta or percreta.Eur J Radiol. 2011 Dec;80(3):729-35. doi: 10.1016/j.ejrad.2010.07.018. Epub 2010 Aug 12. Eur J Radiol. 2011. PMID: 20708361
-
Postpartum hemorrhage.Prim Care. 2012 Mar;39(1):167-87. doi: 10.1016/j.pop.2011.11.009. Prim Care. 2012. PMID: 22309588 Review.
-
Specific second-line therapies for postpartum haemorrhage: a national cohort study.BJOG. 2011 Jun;118(7):856-64. doi: 10.1111/j.1471-0528.2011.02921.x. Epub 2011 Mar 10. BJOG. 2011. PMID: 21392247
-
Intrauterine balloon tamponade in the management of postpartum hemorrhage.Am J Perinatol. 2007 Jun;24(6):359-64. doi: 10.1055/s-2007-984402. Epub 2007 Jun 13. Am J Perinatol. 2007. PMID: 17566947
-
[Intractable postpartum haemorrhages: where is the place of vascular ligations, emergency peripartum hysterectomy or arterial embolization?].Gynecol Obstet Fertil. 2004 Apr;32(4):320-9. doi: 10.1016/j.gyobfe.2004.02.003. Gynecol Obstet Fertil. 2004. PMID: 15123103 Review. French.
Cited by
-
microRNA-1203 targets and silences cyclophilin D to protect human endometrial cells from oxygen and glucose deprivation-re-oxygenation.Aging (Albany NY). 2020 Feb 10;12(3):3010-3024. doi: 10.18632/aging.102795. Epub 2020 Feb 10. Aging (Albany NY). 2020. PMID: 32041924 Free PMC article.
-
Keap1-targeting microRNA-941 protects endometrial cells from oxygen and glucose deprivation-re-oxygenation via activation of Nrf2 signaling.Cell Commun Signal. 2020 Feb 26;18(1):32. doi: 10.1186/s12964-020-0526-0. Cell Commun Signal. 2020. PMID: 32102665 Free PMC article.
-
Gynecological, reproductive and sexual outcomes after uterine artery embolization for post-partum haemorrage.Sci Rep. 2021 Jan 12;11(1):833. doi: 10.1038/s41598-020-80821-0. Sci Rep. 2021. PMID: 33436979 Free PMC article.
-
Ginseng Rh2 protects endometrial cells from oxygen glucose deprivation/re-oxygenation.Oncotarget. 2017 Nov 11;8(62):105703-105713. doi: 10.18632/oncotarget.22390. eCollection 2017 Dec 1. Oncotarget. 2017. PMID: 29285285 Free PMC article.
-
Haemostatic support in postpartum haemorrhage: A review of the literature and expert opinion.Eur J Anaesthesiol. 2023 Jan 1;40(1):29-38. doi: 10.1097/EJA.0000000000001744. Epub 2022 Sep 22. Eur J Anaesthesiol. 2023. PMID: 36131564 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials