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Review
. 2015 Mar;42(1):133-54, ix.
doi: 10.1016/j.clp.2014.10.012. Epub 2014 Nov 27.

Infectious causes of necrotizing enterocolitis

Sarah A Coggins  1 , James L Wynn  2 , Jörn-Hendrik Weitkamp  3
Affiliations
Review

Infectious causes of necrotizing enterocolitis

Sarah A Coggins et al. Clin Perinatol. 2015 Mar.

Abstract

Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency among premature infants. Although a large body of research has focused on understanding its pathogenesis, the exact mechanism has not been elucidated. Of particular interest is the potential causative role of infectious culprits in the development of NEC. A variety of reports describe bacterial, viral, and fungal infections occurring in association with NEC; however, no single organism has emerged as being definitively involved in NEC pathogenesis. In this review, the authors summarize the literature on infectious causes of NEC.

Keywords: Bacteria; Fungi; Necrotizing enterocolitis; Neonate; Virus.

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Figures

Fig. 1
Fig. 1
Clinical decision algorithms. CBC, complete blood cell count; CRP, C-reactive protein; NPO, nil per os (nothing by mouth).
See this image and copyright information in PMC

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