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Review
. 2015 Mar;42(1):177-94, x.
doi: 10.1016/j.clp.2014.10.010. Epub 2014 Nov 25.

New antifungal and antiviral dosing

Kelly C Wade  1 , Heather M Monk  2
Affiliations
Review

New antifungal and antiviral dosing

Kelly C Wade et al. Clin Perinatol. 2015 Mar.

Abstract

Neonatal fungal and viral infections are associated with mortality and neurologic impairment among survivors. Advances in pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial medications have led to improved dosing guidance for neonates. This article discusses the basic PK/PD properties and dosing of the most common antifungal and antiviral medications used in neonates.

Keywords: Acyclovir; Amphotericin; Echinocandin; Fluconazole; Ganciclovir; Neonate.

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Supplementary concepts