Cost-utility of a lifestyle intervention in adolescents and young adults with spastic cerebral palsy

Abstract

Objective: To evaluate the cost-utility of a lifestyle intervention among adolescents and young adults with cerebral palsy.

Design: Single-blind, randomized controlled trial.

Setting: Six university hospital/clinics in the Netherlands.

Participants: Fifty-seven adolescents and young adults with spastic cerebral palsy classified as Gross Motor Functioning Classification System (GMFCS) level I-IV.

Intervention: A 6-month lifestyle intervention consisting of physical fitness training combined with counselling sessions focusing on physical behaviour and sports participation.

Main outcome measures: Data on quality of life, direct medical costs and productivity costs were collected using standardized questionnaires. Quality adjusted life years (QALYs) were derived from the Short-Form 36 questionnaire using the Short-Form 6D.

Results: Quality of life remained stable over time for both groups. No significant differences between groups were found for direct medical costs or productivity costs. A cost-utility ratio of -€23,664 per QALY was found for the lifestyle intervention compared with no treatment.

Conclusion: The results of this study are exploratory, but indicate that implementing a lifestyle intervention for the cerebral palsy population might be cost-effective or cost-saving compared with offering no intervention to improve physical behaviour and fitness. However, the large range of uncertainty for the cost-utility ratio should be taken into account and the results interpreted with caution.