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Case Reports
. 2015 Jan;3(1):50-6.
doi: 10.1002/ccr3.146. Epub 2014 Dec 3.

Malignant peripheral nerve sheath tumor of the third eyelid in a 3-year-old Rhodesian Ridgeback

Franziska Vom Hagen  1 , Gwendolyna Romkes  1 , Olivia Kershaw  2 , J Corinna Eule  1
Affiliations
Case Reports

Malignant peripheral nerve sheath tumor of the third eyelid in a 3-year-old Rhodesian Ridgeback

Franziska Vom Hagen et al. Clin Case Rep. 2015 Jan.

Abstract

A 3-year-old Rhodesian Ridgeback was presented with conjunctivitis, enlargement of the third eyelid and a dorsotemporal deviation of the right eye. A mass within the third eyelid was detected and excised. The histopathologic examination showed a malignant peripheral nerve sheath tumor, which most likely is a neurofibrosarcoma based on immunohistochemistry.

Keywords: Dog; neoplasia; nictitans; orbita; periocular.

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Figures

Figure 1
Figure 1
Clinical picture of a 3-year-old Rhodesian Ridgeback, which was presented with protrusion of the third eyelid. Upon inspection the enlargement of the nictitans and a temporodorsal deviation of the globe were present (A and B).
Figure 2
Figure 2
The third eyelid and the mass appeared grossly to be completely removed by surgery (A) and was sent for histopathologic analysis (B and C).
Figure 3
Figure 3
Low power (A) and high power (B) photomicrographs of hematoxylin and eosin stained sections of the excised tumor within the nictitans. Arrows indicate mitotic figures. Bars: 200 μm (A) and 50 μm (B).
Figure 4
Figure 4
Immunohistochemical staining of the tumor tissue. Virtually all cells were positive for vimentin (A) and up to 50% of the cells were positive for S-100 (B). Bars: 50 μm.
See this image and copyright information in PMC

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