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. 2015 Jul-Aug;70(4):347-50.
doi: 10.2515/therapie/2014218. Epub 2015 Feb 16.

Drugs and Sleep Apneas? A review of the French Pharmacovigilance database

Mélanie Linselle  1 , François Montastruc  1 , Hélène Jantzen  2 , Marie-Blanche Valnet-Rabier  3 , Françoise Haramburu  4 , Antoine Coquerel  5 , Aurore Gouraud  6 , Marie-Christine Perault-Pochat  7 , Haleh Bagheri  1 , Jean-Louis Montastruc  1
Affiliations

Drugs and Sleep Apneas? A review of the French Pharmacovigilance database

Mélanie Linselle et al. Therapie. 2015 Jul-Aug.

Abstract

The present work reviews the case reports of drug-induced sleep apnea recorded in the French pharmacovigilance database. Notifications are very rare (around 1/100 000 notifications). This paper shows that sleep apnea can be aggravated or revealed by some drugs. Main drugs involved were psychotropics (benzodiazepines, neuroleptics) and opioids.

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