RNA: jack of all trades and master of all
- PMID: 25679756
- DOI: 10.1016/j.cell.2015.01.047
RNA: jack of all trades and master of all
Abstract
Noncoding RNAs have regulatory capabilities that evolution harnesses to fulfill diverse functions. Lee et al. show that a noncoding RNA from Epstein-Barr virus recruits a host transcription factor to silence virus gene expression and propose that it does this through base-pairing with nascent viral transcripts.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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EBV noncoding RNA binds nascent RNA to drive host PAX5 to viral DNA.Cell. 2015 Feb 12;160(4):607-618. doi: 10.1016/j.cell.2015.01.015. Epub 2015 Feb 5. Cell. 2015. PMID: 25662012 Free PMC article.
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