Cell migration, freshly squeezed
- PMID: 25679757
- DOI: 10.1016/j.cell.2015.01.053
Cell migration, freshly squeezed
Abstract
Migrating cells exhibit distinct motility modes and can switch between modes based on chemical or physical cues. Liu et al. and Ruprecht et al. now describe how confinement and contractility influence motility mode plasticity and instigate a mode termed stable bleb migration in embryonic and tumor cells.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells.Cell. 2015 Feb 12;160(4):659-672. doi: 10.1016/j.cell.2015.01.007. Cell. 2015. PMID: 25679760
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Cortical contractility triggers a stochastic switch to fast amoeboid cell motility.Cell. 2015 Feb 12;160(4):673-685. doi: 10.1016/j.cell.2015.01.008. Cell. 2015. PMID: 25679761 Free PMC article.
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