Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1989;93(1):195-201.
doi: 10.1016/0300-9629(89)90207-7.

The role of excitatory amino acids in synaptic transmission in the hippocampus

J D Lambert  1 , R S Jones, M Andreasen, M S Jensen, U Heinemann
Affiliations
Review

The role of excitatory amino acids in synaptic transmission in the hippocampus

J D Lambert et al. Comp Biochem Physiol A Comp Physiol. 1989.

Abstract

We have highlighted some aspects of the action of excitatory amino acid transmission in the hippocampus. Fast epsps can be blocked by CNQX to reveal a component of synaptic transmission which is mediated by NMDA receptors. Extracellular recordings of ionic activities show that NMDA and non-NMDA ionophores are permeable to the major monovalent cations, while NMDA ionophores also appear to be permeable to Ca2+. Interactions of agonists applied by iontophoresis may be correlates of phenomena such as LTP, which can be evoked by appropriate synaptic stimulation.

PubMed Disclaimer

Publication types

LinkOut - more resources