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. 1989 Jul 22;2(8656):191-3.
doi: 10.1016/s0140-6736(89)90374-7.

Cultured composite skin grafts: biological skin equivalents permitting massive expansion

J Nanchahal  1 , W R Otto, R Dover, S K Dhital
Affiliations

Cultured composite skin grafts: biological skin equivalents permitting massive expansion

J Nanchahal et al. Lancet. .

Abstract

After assessment in mice, a biological skin equivalent consisting of cultured fibroblasts in a collagen gel overlain with cultured keratinocytes was applied to three patients who had had tattoos excised. In all patients the grafts took well with good cosmetic results and little or no contracture. A biopsy at 4 weeks showed that the central graft area had a fully differentiated epidermis and a mature dermis without adnexae.

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  • Skin equivalents.
    Hancock K, Hackett ME. Hancock K, et al. Lancet. 1989 Aug 19;2(8660):440. doi: 10.1016/s0140-6736(89)90608-9. Lancet. 1989. PMID: 2474732 No abstract available.

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