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Review
. 2015 Feb 16;3(2):141-7.
doi: 10.12998/wjcc.v3.i2.141.

Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair

David J Gerth  1 , Jun Tashiro  1 , Seth R Thaller  1
Affiliations
Review

Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair

David J Gerth et al. World J Clin Cases. .

Abstract

The gold standard of peripheral nerve repair is nerve autograft when tensionless repair is not possible. Use of nerve autograft has several shortcomings, however. These include limited availability of donor tissue, sacrifice of a functional nerve, and possible neuroma formation. In order to address these deficiencies, researchers have developed a variety of biomaterials available for repair of peripheral nerve gaps. We review the clinical studies published in the English literature detailing outcomes and reconstructive options. Regardless of the material used or the type of nerve repaired, outcomes are generally similar to nerve autograft in gaps less than 3 cm. New biomaterials currently under preclinical evaluation may provide improvements in outcomes.

Keywords: Conduit; Nerve tissue; Plastic surgery; Reconstructive surgical procedures; Scaffold.

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References

    1. Terzis J, Faibisoff B, Williams B. The nerve gap: suture under tension vs. graft. Plast Reconstr Surg. 1975;56:166–170. - PubMed
    1. Wang WZ, Crain GM, Baylis W, Tsai TM. Outcome of digital nerve injuries in adults. J Hand Surg Am. 1996;21:138–143. - PubMed
    1. Speidel CC. Studies of Living Nerves III. Phenomena of nerve irritation and recovery, degeneration, and repair. J Comp Neurol. 1935;61:79.
    1. Liu CT, Benda CE, Lewey FH. Tensile strength of human nerves; an experimental physical and histologic study. Arch Neurol Psychiatry. 1948;59:322–336. - PubMed
    1. Miyamoto Y. Experimental study of results of nerve suture under tension vs. nerve grafting. Plast Reconstr Surg. 1979;64:540–549. - PubMed