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Multicenter Study
. 2015 Mar;135(3):424-34.
doi: 10.1542/peds.2014-1774.

Racial-ethnic disparities in management and outcomes among children with type 1 diabetes

Steven M Willi  1 , Kellee M Miller  2 , Linda A DiMeglio  3 , Georgeanna J Klingensmith  4 , Jill H Simmons  5 , William V Tamborlane  6 , Kristen J Nadeau  7 , Julie M Kittelsrud  8 , Peter Huckfeldt  9 , Roy W Beck  10 , Terri H Lipman  1 ; T1D Exchange Clinic Network
Collaborators, Affiliations
Multicenter Study

Racial-ethnic disparities in management and outcomes among children with type 1 diabetes

Steven M Willi et al. Pediatrics. 2015 Mar.

Abstract

Background and objectives: Previous research has documented racial/ethnic disparities in diabetes treatments and outcomes. It remains controversial whether these disparities result from differences in socioeconomic status (SES) or other factors. We examined racial/ethnic disparities in therapeutic modalities and diabetes outcomes among the large number of pediatric participants in the T1D Exchange Clinic Registry.

Methods: The cohort included 10 704 participants aged <18 years with type 1 diabetes for ≥1 year (48% female; mean age: 11.9 ± 3.6 years; diabetes duration: 5.2 ± 3.5 years). Diabetes management and clinical outcomes were compared among 8841 non-Hispanic white (white) (83%), 697 non-Hispanic black (black) (7%), and 1166 Hispanic (11%) participants. The population included 214 high-income black and Hispanic families.

Results: Insulin pump use was higher in white participants than in black or Hispanic participants (61% vs 26% and 39%, respectively) after adjusting for gender, age, diabetes duration, and SES (P < .001). Mean hemoglobin A1c was higher (adjusted P < .001) in black participants than in white or Hispanic participants (9.6%, 8.4%, and 8.7%). More black participants experienced diabetic ketoacidosis and severe hypoglycemic events in the previous year than white or Hispanic participants (both, P < .001). There were no significant differences in hemoglobin A1c, diabetic ketoacidosis, or severe hypoglycemia between white and Hispanic participants after adjustment for SES.

Conclusions: Even after SES adjustment, marked disparities in insulin treatment method and treatment outcomes existed between black versus Hispanic and white children within this large pediatric cohort. Barriers to insulin pump use and optimal glycemic control beyond SES should be explored in all ethnic groups.

Keywords: diabetes management; ethnicity; glycemic control; race; type 1 diabetes.

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Figures

FIGURE 1
FIGURE 1
Insulin delivery regimen/method according to age and race/ethnicity. White section, pump users; black section, multiple daily injections; black and white striped section, fixed dose users.
FIGURE 2
FIGURE 2
Mean HbA1c level according to race/ethnicity and insulin regimen/method. MDI, multiple daily injections. White bar, non-Hispanic white; black bar, non-Hispanic black; black and white striped bar, Hispanic.
See this image and copyright information in PMC

Comment in

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