Candidate gene methylation studies are at high risk of erroneous conclusions
- PMID: 25687462
- PMCID: PMC5503464
- DOI: 10.2217/epi.14.70
Candidate gene methylation studies are at high risk of erroneous conclusions
Keywords: DNA methylation; candidate gene study; false discoveries; methylome-wide association study; principal component analysis.
References
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- Hsiung DT, Marsit CJ, Houseman EA, et al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2007;16(1):108–114. - PubMed
-
- Lim U, Song MA. Dietary and lifestyle factors of DNA methylation. Methods Mol Biol. 2012;863:359–376. - PubMed
-
- van den Oord EJ, Sullivan PF. False discoveries and models for gene discovery. Trends Genet. 2003;19(10):537–542. - PubMed
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