Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Feb 17;108(4):785-786.
doi: 10.1016/j.bpj.2014.12.032.

Chromosome, cell cycle, and entropy

Suckjoon Jun  1
Affiliations
Comment

Chromosome, cell cycle, and entropy

Suckjoon Jun. Biophys J. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Illustration by David Goodsell depicting the interior of E. coli during multifork replication under fast growth conditions based on Youngren et al. (1). The illustration includes supercoiled DNA during replication (yellow), nucleoid-associated proteins (varying shades of amber), cytoplasm (blue), ribosomes (purple), RNA polymerases (dark orange), and RNA (pink). Two overlapping cell cycles are taking place with each daughter cell containing two origins of replication. The multifork E. coli chromosome is like a branched donut. (Inset, top right) E. coli chromosomes during multifork replication, fluorescently labeled with functional HU-mCherry (6).
See this image and copyright information in PMC

Comment on

References

    1. Youngren B., Nielsen H.J., Austin S. The multifork Escherichia coli chromosome is a self-duplicating and self-segregating thermodynamic ring polymer. Genes Dev. 2014;28:71–84. - PMC - PubMed
    1. Luijsterburg M.S., White M.F., Dame R.T. The major architects of chromatin: architectural proteins in bacteria, archaea and eukaryotes. Crit. Rev. Biochem. Mol. Biol. 2008;43:393–418. - PubMed
    1. Asakura S., Oosawa F. On interaction between two bodies immersed in a solution of macromolecules. J. Chem. Phys. 1954;22:1255.
    1. Odijk T. Osmotic compaction of supercoiled DNA into a bacterial nucleoid. Biophys. Chem. 1998;73:23–29. - PubMed
    1. Cunha S., Woldringh C.L., Odijk T. Polymer-mediated compaction and internal dynamics of isolated Escherichia coli nucleoids. J. Struct. Biol. 2001;136:53–66. - PubMed

MeSH terms