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. 2015 Mar;26(3):129.
doi: 10.1007/s10856-015-5475-6. Epub 2015 Feb 19.

Antibacterial and non-cytotoxic effect of nanocomposites based in polyethylene and copper nanoparticles

L A Tamayo  1 , P A Zapata, F M Rabagliati, M I Azócar, L A Muñoz, X Zhou, G E Thompson, M A Páez
Affiliations

Antibacterial and non-cytotoxic effect of nanocomposites based in polyethylene and copper nanoparticles

L A Tamayo et al. J Mater Sci Mater Med. 2015 Mar.

Abstract

In this study, an antibacterial, but not cytotoxic nanomaterial based on polyethylene and copper nanoparticles was prepared by in situ polymerization. PE-CuNps nanocomposites against Escherichia coli, completely suppressed the number of live bacteria after 12 h incubation compared to neat PE. TEM images showed that nanocomposites damage the plasma membrane of the bacteria, revealing a bacteriolytic effect. Toxic effects of copper nanoparticles on viability of neuroblastoma line cell also was evaluated, revealing a non cytotoxic effect for the doses used, showing that this nanocomposite is a ideal material for medical devices.

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