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Comparative Study
. 2015 Oct;17(5):620-4.
doi: 10.1007/s11307-014-0813-5.

Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

Kate I Rewers  1 , Svend Hvidsten  2 , Oke Gerke  2   3 , Søren Schifter  2
Affiliations
Comparative Study

Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software

Kate I Rewers et al. Mol Imaging Biol. 2015 Oct.

Abstract

Purpose: The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.

Procedures: Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.

Results: Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.

Conclusions: We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.

Keywords: ROI; Reference range; Tc-99m-MAG3 renography.

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