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. 2014 Jul-Sep;18(3):275-7.

Eosinophilic ascites, as a rare presentation of eosinophilic gastroenteritis

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Eosinophilic ascites, as a rare presentation of eosinophilic gastroenteritis

L Cuko et al. Hippokratia. 2014 Jul-Sep.

Abstract

Background: Eosinophilic ascites is the most unusual presentation of eosinophilic gastroenteritis (EGE), caused by edema and eosinophilic inflammation of the small bowel wall's serosal layer.

Case report: We report the case of a 37-year-old woman, who presented with diffuse abdominal pain, nausea, abdominal distension, moderate ascites and diarrhea of two weeks duration. The rest of physical and clinical examination was unremarkable, and her past medical history was uneventful. Magnetic Resonance Imaging showed the presence of ascites and diffuse thickening of small bowel wall, but did not detect a primary malignancy in the abdominal cavity; and no signs of portal hypertension or liver damage. Laboratory test results revealed essential peripheral blood eosinophilia, elevated serum IgE and marked increase of eosinophils in the abdominal fluid. Treatment with corticosteroids normalized laboratory tests results, and the ascites resolved immediately.

Conclusions: EGE is a rare entity and it should be kept in mind in patients of unexplained ascites. The absence of primary malignancy on imaging, coupled with marked increase of fluid esinophilia and immediate response to treatment with steroids, confirm indirectly the diagnosis of EGE. Hippokratia 2014; 18 (3): 275-277.

Keywords: Eosinophilic gastroenteritis; ascites; corticosteroids; magnetic resonance imaging.

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Figures

Figure 1
Figure 1. Cytology specimen showing eosinophils in 94% (Giemsa, x 40).
Figure 2
Figure 2. Cytology specimen showing eosinophils in 94% (Giemsa, x 40).
Figure 3
Figure 3. Magnetic resonance imaging, T2-weighted image (coronal view) showing moderate ascites and normal liver structure.
Figure 4
Figure 4. Magnetic resonance imaging, T2- weighted image (sagital view) showing moderate ascites and normal ovary.
Figure 5
Figure 5. Magnetic resonance imaging, T2-weighted image with fat saturation (axial view) showing small bowel thickening and submucosal edema.
Figure 6
Figure 6. Magnetic resonance imaging, 3D gradient echo images after administration of intravenous contrast medium (axial view) showing small bowell thickening with mild enhancment.

References

    1. Zhou HB, Chen JM, Du Q. Eosinophilic gastroenteritis with ascites and hepatic dysfunction. World J Gastroenterol. 2007;13:1303–1305. - PMC - PubMed
    1. Agostina A, Parenzi A. [Eosiniphilic gastroenteritis. A case with predominant involvement of mucosal and muscular layers] Minerva Med. 1994;85:12: 655–658. - PubMed
    1. Hepburn IS, Sridhar S, Schade RR. Eosinophilic ascites, an unusual presentation of eosinophilic gastroenteritis: A case report and review. World J Gastrointest Pathophysiol. 2010;1:166–170. - PMC - PubMed
    1. Talley NJ, Shorter RG, Phillips SF, Zinsmeister AR. Eosinophilic gastroenteritis: a clinicopathological study of patients with disease of the mucosa, muscle layer and subserosal tissue. Gut. 1990;31:54–58. - PMC - PubMed
    1. Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID) J Allergy Clin Immunol. 2004;113:11–28. - PubMed

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