Comment
doi: 10.1016/j.neuron.2015.02.004.
Loosening pain's grip by tightening TRPV1-TRPA1 interactions
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- PMID: 25695265
- DOI: 10.1016/j.neuron.2015.02.004
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Loosening pain's grip by tightening TRPV1-TRPA1 interactions
Neuron.
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Abstract
TRPA1 and TRPV1 are ion channels crucial for pain sensation. In this issue of Neuron, Weng et al. (2015) demonstrate that the activity of TRPA1-TRPV1 heteromers is governed by Tmem100 and that disabling Tmem100 may be a novel pharmacologic strategy to combat pain.
Copyright © 2015 Elsevier Inc. All rights reserved.
Comment on
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