Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2006 Nov;14(11):381-387.

Angiotensin II receptor antagonists (AT1-blockers, ARBs, sartans): similarities and differences

P A van Zwieten

Angiotensin II receptor antagonists (AT1-blockers, ARBs, sartans): similarities and differences

P A van Zwieten. Neth Heart J. 2006 Nov.

Abstract

A survey is presented of the registered non-peptidergic angiotensin II receptor antagonists (AT1 blockers, ARBs, sartans) and their general properties and similarities. Accordingly, their receptor profile, pharmacokinetic and therapeutic applications are discussed. In addition, attention is paid to the individual characteristics of the AT1 blockers now available. A few components of this category offer additional potentially beneficial properties, owing to their pharmacological or metabolic characteristics. Such additional properties are critically discussed for eprosartan, losartan, telmisartan and valsartan.

Keywords: AT1 receptors; angiotensin II receptor antagonists; insulin sensitisation; renin-angiotensin system.

PubMed Disclaimer

References

    1. Circulation. 2002 Aug 6;106(6):672-8 - PubMed
    1. N Engl J Med. 2001 Sep 20;345(12 ):870-8 - PubMed
    1. N Engl J Med. 2003 Nov 13;349(20):1893-906 - PubMed
    1. N Engl J Med. 2004 Nov 4;351(19):1952-61 - PubMed
    1. Expert Opin Investig Drugs. 1998 May;7(5):741-51 - PubMed

LinkOut - more resources