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Meta-Analysis
. 2015 May;25(5):860-78.
doi: 10.1007/s11695-015-1581-2.

Bariatric surgery in morbidly obese adolescents: a systematic review and meta-analysis

Givan F Paulus  1 , Loes E G de Vaan, Froukje J Verdam, Nicole D Bouvy, Ton A W Ambergen, L W Ernest van Heurn
Affiliations
Meta-Analysis

Bariatric surgery in morbidly obese adolescents: a systematic review and meta-analysis

Givan F Paulus et al. Obes Surg. 2015 May.

Abstract

Pubmed, Embase, and Cochrane were systematically reviewed for available evidence on bariatric surgery in adolescents. Thirty-seven included studies evaluated the effect of laparoscopic adjustable gastric banding (LAGB), Roux-en-Y gastric bypass (RYGB), or laparoscopic sleeve gastrectomy (LSG) in patients ≤18 years old. Fifteen of 37 studies were prospective, including one RCT. Mean body mass index (BMI) loss after LAGB was 11.6 kg/m(2) (95% CI 9.8-13.4), versus 16.6 kg/m(2) (95% CI 13.4-19.8) after RYGB and 14.1 kg/m(2) (95% CI 10.8-17.5) after LSG. Two unrelated deaths were reported after 495 RYGB procedures. All three bariatric procedures result in substantial weight loss and improvement of comorbidity with an acceptable complication rate, indicating that surgical intervention is applicable in appropriately selected morbidly obese adolescents.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Search terms: full Pubmed search
Fig. 2
Fig. 2
Search diagram: paper retrieval schematic
Fig. 3
Fig. 3
Meta-analysis: forest plot for BMI loss with 95 % confidence intervals and summarized means after LAGB, RYGB, and LSG
Fig. 4
Fig. 4
Funnel plots: funnel plots of SEM of BMI loss versus BMI loss for the assessment of heterogeneity in outcome reporting. Dots outside the 95 % pseudo confidence limits are indicative of heterogeneity
See this image and copyright information in PMC

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