Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation
- PMID: 2570
- DOI: 10.1007/BF02462790
Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation
Abstract
A method for the chemical fixation of the enzyme GABA-transaminase in nervous tissue is described. It is shown that after perfusion with a formaldehyde/glutaraldehyde fixative, activity of the enzyme in cerebellar cortex is demonstrable whilst cellular morphology is preserved. Results from the improved technique have shown new sites of GABA-transaminase activity in cerebellar cortex. In view of these results a special function for glial cells in this area of brain has been suggested.
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