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. 1976 Feb 26;46(3):261-8.
doi: 10.1007/BF02462790.

Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation

J C Hyde, N Robinson

Improved histological localization of GABA-transaminase activity in rat cerebellar cortex after aldehyde fixation

J C Hyde et al. Histochemistry. .

Abstract

A method for the chemical fixation of the enzyme GABA-transaminase in nervous tissue is described. It is shown that after perfusion with a formaldehyde/glutaraldehyde fixative, activity of the enzyme in cerebellar cortex is demonstrable whilst cellular morphology is preserved. Results from the improved technique have shown new sites of GABA-transaminase activity in cerebellar cortex. In view of these results a special function for glial cells in this area of brain has been suggested.

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References

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