Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney
Affiliations
- PMID: 2570449
Item in Clipboard
Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney
Rev Esp Fisiol.
1989 Jun.
Abstract
The participation of beta 1-adrenoceptor on renin secretion was studied in perfused rat kidney. Administration of propranolol, inhibited the renin release mediated by isoproterenol. Likewise, metoprolol and practolol, showed a similar potency to propranolol in inhibiting isoproterenol-induced renin secretion. These results suggest that the for isoproterenol-induced renin release in rats is a beta 1-type adrenoceptor.
Similar articles
-
Beta adrenergically mediated release of renin in the dog is not confined to either beta-1 or beta-2 adrenoceptors.J Pharmacol Exp Ther. 1982 Sep;222(3):606-11. J Pharmacol Exp Ther. 1982. PMID: 6125584
-
Effects of selective and nonselective beta adrenergic agents on renin secretion in isolated perfused rat kidney.J Pharmacol Exp Ther. 1980 Jan;212(1):34-8. J Pharmacol Exp Ther. 1980. PMID: 6101342
-
Comparison of the effects on renin release of beta adrenergic antagonists with differing properties.J Clin Invest. 1974 Dec;54(6):1413-9. doi: 10.1172/JCI107888. J Clin Invest. 1974. PMID: 4154950 Free PMC article.
-
Sympathetic control of renin release.Annu Rev Pharmacol Toxicol. 1982;22:167-92. doi: 10.1146/annurev.pa.22.040182.001123. Annu Rev Pharmacol Toxicol. 1982. PMID: 6282185 Review.
-
[Beta-blockaders in the treatment of arterial hypertension. Part I. Pharmacologic, hemodynamic and metabolic aspects].Coeur Med Interne. 1978 Jan-Mar;17(1):113-22. Coeur Med Interne. 1978. PMID: 25158 Review. French. No abstract available.