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. 1989 Jun;45(2):195-8.

Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney

J M Haro  1 , F Vargas, M A Castillo, L García-Torres, D Acuña
Affiliations
  • PMID: 2570449

Effects of selective and non-selective beta 1-blockade on renin secretion in the isolated rat kidney

J M Haro et al. Rev Esp Fisiol. 1989 Jun.

Abstract

The participation of beta 1-adrenoceptor on renin secretion was studied in perfused rat kidney. Administration of propranolol, inhibited the renin release mediated by isoproterenol. Likewise, metoprolol and practolol, showed a similar potency to propranolol in inhibiting isoproterenol-induced renin secretion. These results suggest that the for isoproterenol-induced renin release in rats is a beta 1-type adrenoceptor.

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