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. 2014 Oct-Dec;9(4):444-8.
doi: 10.4103/2008-322X.150814.

Long term efficacy of repeat selective laser trabeculoplasty

Albert S Khouri  1 , Hamed B Lari  1 , Tamara L Berezina  1 , Barry Maltzman  2 , Robert D Fechtner  1
Affiliations

Long term efficacy of repeat selective laser trabeculoplasty

Albert S Khouri et al. J Ophthalmic Vis Res. 2014 Oct-Dec.

Abstract

Purpose: To evaluate long term intraocular pressure (IOP) control after repeat selective laser trabeculoplasty (SLT).

Methods: This single center study retrospectively reviews the electronic medical records of patients with open angle glaucoma undergoing repeat SLT. Eyes with prior argon laser trabeculoplasty, or incisional surgery before or during the study period were excluded. Demographics, laser parameters, number of glaucoma medications and IOP at baseline and after 1, 4, 8, 12, 18 and 24 months were collected. The percentage of subjects with IOP reduction >20% and ≥15% from baseline was determined.

Results: A total of 45 eyes of 25 subjects with mean age of 73 ± 9 years undergoing repeat SLT were included. Repeat SLT was performed at a mean interval of 28.3 ± 12.7 months after initial treatment. Mean IOP reductions were statistically significant with repeat SLT as compared to baseline at 1, 4, 8, 12, 18 and 24 months' follow-up. Change in IOP after first and repeat SLT were comparable at most time points except at 4, 8 and 12 months when initial treatment had yielded significantly greater reductions. At 24 months, 29% and 39% of eyes achieved IOP reduction >20% and ≥15% respectively after repeat SLT as compared to 36% and 54% of eyes following initial treatment (P > 0.05).

Conclusion: Repeat SLT is effective in lowering IOP up to 24 months. Long term IOP control was achieved in 29-39% of eyes following repeat treatment in this cohort of patients.

Keywords: Glaucoma Treatment; Intraocular Pressure; Repeat Selective Laser Trabeculoplasty.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Mean intraocular pressure (IOP) at all time points following first and repeat SLT. *Mean IOP was statistically lower than baseline (P< 0.05), #mean IOP statistically different between first and repeat SLT.
Figure 2
Figure 2
Box and Whisker plot denoting intraocular pressure median, upper and lower quartiles, and range at different time points.
Figure 3
Figure 3
Kaplan–Meier survival showing 20% and 15% plots for first and repeat SLT over 24 months.
See this image and copyright information in PMC

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